Post-inflammatory

Hyperpigmentation Laser Treatments in Maryland

Post-inflammatory hyperpigmentation (PIH) happens when your skin makes extra melanin after it has been irritated or injured.

What is Post-inflammatory hyperpigmentation (PIH)?

This skin condition can develop on irritated and injured skin. It is important to note that PIH is not scar development. Instead, it is the manufacturing of pigment in your skin in response to an injury or irritation. Your body makes extra pigment called melanin that can appear as dark red, tan, brown, or blue-gray patches on your skin.

PIH is more common than most people realize. A 2024 international survey of nearly 48,000 participants, published in the Journal of the American Academy of Dermatology, found that 15% of the global population reports experiencing PIH. People with deeper skin tones are particularly affected. If you’ve been struggling with stubborn dark spots and can’t seem to shake them, there are real solutions available right here in the Baltimore area.

Common Causes For Skin Hyperpigmentation

The most common causes of hyperpigmentation are acne, eczema, or infections such as impetigo. Other reported causes are:

  • Razor burns
  • Bug bites
  • Infections
  • Burns
  • Allergic reactions

Many instances of skin inflammation, whether from a breakout, an ingrown hair or a sunburn, have the potential to trigger excess melanin production as your skin heals. The darker your natural skin tone, the more pronounced and longer-lasting that response tends to be.

Effective Treatments for PIH

Treating post-inflammatory hyperpigmentation (PIH) typically involves a combination of topical care and professional procedures in order to fade discoloration and even out the skin tone. The most effective treatments for PIH include:

  • Laser Treatments (PIQO4): Advanced laser technology, like the PIQO4, safely breaks down excess pigment in the skin without harming the surrounding tissue, making it effective for all skin types.
  • Topical Agents: Using over-the-counter products with ingredients like glycolic acid, niacinamide and tranexamic acid to exfoliate the skin and inhibit pigment production.
  • Sunscreen: Daily application of a broad-spectrum sunscreen is essential to prevent existing spots from darkening and new ones from forming.
  • Prescription Creams: For more stubborn PIH, a dermatologist may prescribe stronger formulations of alpha hydroxy acids (AHAs) or retinoids.
  • Chemical Peels: A professional peel uses a chemical solution to remove the outer layers of skin, revealing a smoother and more evenly pigmented surface below.

Our doctors use the PIQO4 laser to fade persistent hyperpigmentation. This skin treatment is safe for all skin types. The laser breaks up the pigment. It often requires more than one treatment, depending on the persistence of the case. They also prescribe Tranexamic Acid (TXA) to be applied between treatments to accelerate the reduction of skin discoloration.

For patients dealing with skin discoloration beyond PIH, such as melasma or sun damage, our team may recommend broadband light (BBL) therapy or other laser treatments as part of a broader skin care plan.

Who Is a Good Candidate for Hyperpigmentation Laser Treatment?


The PIQO4 is one of the more versatile lasers in our practice because it’s been proven safe and effective across all skin types, including darker tones that historically required more caution with laser energy. 

You may be a strong candidate if you:

  • Have PIH that has persisted for more than three to six months despite topical care
  • Have dark spots stemming from acne, eczema, a burn or another inflammatory skin event
  • Are not currently pregnant or nursing
  • Are willing to commit to consistent sun protection before, during and after your treatment series

Patients with active acne should work to get breakouts under control before beginning laser treatment, since new inflammation can trigger fresh pigmentation and work against your results. This is something we discuss openly during your consultation to make sure we agree on an effective, practical plan.

Your Hyperpigmentation Laser Treatment Experience at Profile MD

Here’s what the hyperpigmentation laser experience typically looks like from start to finish:

Your Consultation

One of our experienced physicians will take a close look at your skin, ask about the history of your hyperpigmentation and review any treatments you’ve tried before. We’ll also ask about your skincare routine, sun exposure habits and lifestyle, because those factors directly influence how we approach your treatment plan.

If the PIQO4 is the right fit, we’ll outline how many sessions you’re likely to need and what to pair it with between appointments.

Your Treatment

On the day of your laser session, we’ll clean the treatment area and provide you with protective eyewear. The PIQO4 handpiece is then passed over the treatment areas, where it delivers rapid pulses of light energy that fragment melanin deposits beneath the skin’s surface. Most patients describe the sensation as a series of quick snaps that are noticeable but very manageable. Sessions are typically brief, usually 15-30 minutes, depending on the size of the area being treated.

Aftercare, Recovery and Results

Recovery from PIQO4 treatments is straightforward. Most patients return to their regular schedule the same day. For the first several days post-treatment, we recommend:

  • Keeping the area clean with a gentle, fragrance-free cleanser
  • Applying a calming, hydrating moisturizer to support healing
  • Wearing SPF 30 or higher sunscreen every single day, rain or shine
  • Avoiding direct sun exposure and heat (saunas, hot yoga) for at least a week

You may notice that treated dark spots appear slightly darker in the days immediately following your session before they begin to shed and fade. This is a normal and expected part of the process. Your skin is clearing the fragmented pigment out from the inside. Don’t pick at the area; your skin needs to do the work.

Results build progressively over your treatment series. Most patients see meaningful improvement after two to three sessions, though more stubborn or deeply set pigmentation may require additional visits. Between sessions, your prescribed TXA regimen helps suppress new melanin production so each laser treatment can build on the last.

Frequently Asked Questions About Hyperpigmentation Treatment

The number of sessions varies by patient. Mild, superficial PIH may respond well in two to three treatments, while more stubborn or deeply deposited pigmentation can require four to six sessions. We will give you a realistic estimate during your consultation based on the depth, age and location of your discoloration. Sessions are typically spaced four to six weeks apart to allow your skin to recover and clear treated pigment fully between visits.
Yes. The PIQO4 was specifically designed to be safe and effective across all Fitzpatrick skin types, including deeper tones (types IV through VI) that require extra precision with laser energy. This is particularly relevant for our melanin-rich patients who are disproportionately affected by PIH. Our providers are trained to calibrate pulse duration and energy settings for each patient’s specific skin type, which minimizes the risk of post-treatment irritation.
They’re related but still distinct. PIH is triggered by a specific inflammatory event, like a breakout, a bug bite, or a burn. Melasma is driven primarily by hormonal factors and UV exposure, often appearing symmetrically across the cheeks and forehead. Sun spots (solar lentigines) are caused by cumulative UV damage over time. All three involve excess melanin, but they respond somewhat differently to treatment. Our providers can help identify exactly what you’re dealing with and recommend the most appropriate approach.
Laser treatment clears the existing excess pigment, but it doesn’t prevent your skin from producing new pigmentation if the underlying trigger isn’t managed. That’s why sun protection is non-negotiable. UV exposure is one of the biggest drivers of melanin production. If acne or eczema caused your PIH, keeping those conditions under control is equally important. With the right maintenance routine and a good sunscreen habit, results can last for years.

Absolutely, and in many cases, a combination approach delivers better results than any single treatment alone. Patients addressing PIH often benefit from pairing PIQO4 sessions with a professional chemical peel to accelerate surface exfoliation, or with medical-grade topicals from our skincare line to suppress pigment production between visits. If you’re also dealing with texture, redness or sun damage alongside your PIH, BBL Hero or MOXI may be worth discussing as complementary treatments.

The Profile MD Beauty Club membership is a great way to receive our treatments at a discount, making consistent care easy to manage.

Most patients describe the PIQO4 as feeling like a series of quick rubber band snaps on the skin. It’s a brief, noticeable sensation that most people find easy to tolerate. If you’re particularly sensitive, let us know at your consultation and we will present you with some options to make you more comfortable during treatment.

Hyperpigmentation Laser Treatment Before & After Photos

EXPERIENCE MATTERS

FREE CONSULTATION

With years of medical experience our doctors, Dr. Jared Mallalieu and Dr. Ross VanAntwerp, specialize in bringing out the best in people through our unique laser and cosmetic procedures. Get in touch with us for your free, no-obligation consultation.

If you’re in Severna Park, Annapolis, Baltimore or anywhere in the surrounding area, Profile MD offers free consultations to discuss your skin and map out a treatment plan that fits your life. Dr. VanAntwerp, Dr. Mallalieu and our full clinical team are here to give you an honest picture of what laser treatment can do for you

Schedule your free consultation today at profilemd.com/contact or call us at 410-544-4600.

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